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Article

Evidence for epigenetic maintenance of Ly49a monoallelic gene expression.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2006

Rouhi Arefeh, Gagnier Liane, Takei Fumio, Mager Dixie L

Abstract excerpt

Although structurally unrelated, the human killer cell Ig-like (KIR) genes and the rodent lectin-like Ly49 genes serve similar functional roles in NK cells. Moreover, both gene families display variegated, monoallelic expression patterns established at the transcriptional level. DNA methylation has been shown to play an important role in maintenance of expression patterns of KIR genes, which have CpG island...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16493057
DOI: 10.4049/jimmunol.176.5.2991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for epigenetic maintenance of Ly49a monoallelic gene expression.PMID 16493057Read ↗

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