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Article

Ly49 receptors: evolution, genetic diversity, and impact on immunity.

Immunological reviews - 1 Sept 2015

Rahim Mir Munir A, Makrigiannis Andrew P

Abstract excerpt

Natural killer (NK) cells express cell surface receptors that recognize class I major histocompatibility complex (MHC-I) molecules to distinguish between healthy and unhealthy cells. The multigenic and polymorphic nature of the MHC-I genes has influenced the convergent evolution of similarly polymorphic and diversified NK cell receptor families: the C-type lectin-like Ly49 receptors in mice, and the killer cell...

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Share to Evolution, Molecular
Share to Genetic Variation
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Killer Cells, Natural

Share to Receptors, KIR

Source

Identifiers

PMID: 26284475
DOI: 10.1111/imr.12318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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