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Article

Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors.

Genes & development - 1 Mar 2006

Wang Lei, Rajan Harini, Pitman Jeffrey L, McKeown Michael, Tsai Chih-Cheng

Abstract excerpt

Drosophila Tailless (Tll) is an orphan nuclear receptor involved in embryonic segmentation and neurogenesis. Although Tll exerts potent transcriptional repressive effects, the underlying molecular mechanisms have not been determined. Using the established regulation of knirps by tll as a paradigm, we report that repression of knirps by Tll involves Atrophin, which is related to vertebrate Atrophin-1 and...

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Identifiers

PMID: 16481466
DOI: 10.1101/gad.1393506
PMCID: PMC1410805

Genes

ADA2
HDAC1
MTA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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