Article
Allele frequency distributions in pooled DNA samples: applications to mapping complex disease genes.
Genome research - 1 Feb 1998
Shaw S H, Carrasquillo M M, Kashuk C, Puffenberger E G, Chakravarti A
Abstract excerpt
Genetic studies of complex hereditary disorders require for their mapping the determination of genotypes at several hundred polymorphic loci in several hundred families. Because only a minority of markers are expected to show linkage and association in family data, a simple screen of genetic mark...
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