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Article

Validation of pooled genotyping on the Affymetrix 500 k and SNP6.0 genotyping platforms using the polynomial-based probe-specific correction.

BMC genetics - 14 Dec 2009

Anantharaman Ramani, Chew Fook Tim

Abstract excerpt

BACKGROUND: The use of pooled DNA on SNP microarrays (SNP-MaP) has been shown to be a cost effective and rapid manner to perform whole-genome association evaluations. While the accuracy of SNP-MaP was extensively evaluated on the early Affymetrix 10 k and 100 k platforms, there have not been as many similarly comprehensive studies on more recent platforms. In the present study, we used the data generated from the...

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Identifiers

PMID: 20003400
DOI: 10.1186/1471-2156-10-82
PMCID: PMC2806376

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