Article
Utility of thrombin-generation assay in the screening of factor V G1691A (Leiden) and prothrombin G20210A mutations and protein S deficiency.
Clinical chemistry - 1 Apr 2006
Hézard Nathalie, Bouaziz-Borgi Lobna, Remy Marie-Geneviève, Nguyen Philippe
Abstract excerpt
BACKGROUND: The thrombin-generation assay has a variety of clinical uses, including diagnosis of thromboembolism-related disease, and particular profiles are associated with thrombophilic risk factors. The aim of this study was to evaluate the use of this assay in screening and identifying patients who require specific thrombophilic testing. METHODS: We used a 2-step approach to perform specific thrombophilic...
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