Article
Thrombin generation and phenotypic correlation in haemophilia A.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 2005
Beltrán-Miranda C P, Khan A, Jaloma-Cruz A R, Laffan M A
Abstract excerpt
The clinical phenotype of patients with haemophilia A (HA) often differs between individuals with the same factor VIII (FVIII) gene defect (e.g. within the same family) or the same coagulant activity of FVIII (FVIII:C). We proposed that because the thrombin generation assay in platelet-poor plasma of HA patients provides more information [peak thrombin concentration, endogenous thrombin potential (ETP), rate of...
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