Article
Prothrombin activation is increased among asymptomatic carriers of the prothrombin G20210A and factor V Arg506Gln mutations.
Thrombosis and haemostasis - 1 Sept 2000
Bauer K A, Humphries S, Smillie B, Li L, Cooper J A, Barzegar S, Rosenberg R D, Miller G J
Abstract excerpt
The risk of venous thrombosis is increased in individuals who carry specific genetic abnormalities in blood coagulation proteins. Among Caucasians, the prothrombin G20210A and factor V Arg506Gln (FV R506Q) mutations are the most prevalent defects identified to date. We evaluated their influence on markers of coagulation activation among participants in the Second Northwick Park Heart Study, which recruited...
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