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Article

Thrombin generation as an intermediate phenotype for venous thrombosis.

Thrombosis and haemostasis - 1 Jan 2010

Segers Olivier, van Oerle René van, ten Cate Hugo ten, Rosing Jan, Castoldi Elisabetta

Abstract excerpt

In vitro thrombin generation, which reflects an individual's plasma coagulation potential and has been shown to correlate with the risk of venous thromboembolism (VTE), might represent a useful intermediate phenotype for the genetic dissection of VTE. As a proof of principle, we have investigated whether the thrombin generation assay can detect changes in the haemostatic balance associated with common genetic...

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PMID: 20062924
DOI: 10.1160/TH09-06-0356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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