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Article

Analysis of ras gene mutations in rainbow trout liver tumors initiated by aflatoxin B1.

Molecular carcinogenesis - 1 Jan 1991

Chang Y J, Mathews C, Mangold K, Marien K, Hendricks J, Bailey G

Abstract excerpt

The suspect human hepatocarcinogen aflatoxin B1 (AFB1) is a well-known potent initiator of hepatic tumors in rainbow trout (Oncorhynchus mykiss). Both hepatocellular carcinomas and mixed hepatocellular/cholangiocellular carcinomas are induced by AFB1 in trout, with the mixed form predominating. We previously isolated two c-ras genes from trout liver cDNA, and in the present study we analyzed DNA from 14...

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PMID: 1645972
DOI: 10.1002/mc.2940040206

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AGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of ras gene mutations in rainbow trout liver tumors initiated by aflatoxin B1.PMID 1645972Read ↗

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