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Article

Kinds of mutations induced by aflatoxin B1 in a shuttle vector replicating in human cells transiently expressing cytochrome P4501A2 cDNA.

Molecular carcinogenesis - 1 Jan 1992

Trottier Y, Waithe W I, Anderson A

Abstract excerpt

Transient expression of rat liver cytochrome P450lA2 cDNA was combined with the use of a shuttle vector as a mutational target to determine the frequency and types of mutation caused by the conversion of aflatoxin B1 into genotoxic metabolites within human cells. Ad293 cells were first transfected with p91-lA2, a rat liver P450lA2 cDNA expression vector, or with p91-lA2(i) (a control vector that has the P450 cDNA...

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PMID: 1326989
DOI: 10.1002/mc.2940060209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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