Article
ras oncogene mutations in diethylnitrosamine-induced hepatic tumors in medaka (Oryzias latipes), a teleost fish.
Mutation research - 5 Aug 2003
Liu Zi, Kullman Seth W, Bencic David C, Torten Michael, Hinton David E
Abstract excerpt
Medaka fish are an established non-mammalian research model for the study of liver carcinogenesis and exposure to environmental pollutants. Studies have emphasized the development of hepatic neoplasms in medaka following exposure to model carcinogens. To date however, little information is known regarding the mechanisms underlying initiation of hepatic tumors in this species. The aim of this study was to relate...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Mutational Analysis
- Diethylnitrosamine
- Genes, ras
- Liver Neoplasms, Experimental
- Molecular Sequence Data
- Mutation
- Oryzias