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Two cases of ras mutation associated with liver hyperplasia in dragonets (Callionymus lyra) exposed to polychlorinated biphenyls and polycyclic aromatic hydrocarbons.

Molecular carcinogenesis - 1 Feb 1998

Vincent F, de Boer J, Pfohl-Leszkowicz A, Cherrel Y, Galgani F

Abstract excerpt

ras gene activation in a naturally exposed feral fish population may prove to be a particularly sensitive genetic marker of malignancy. The aim of this study was to relate our current knowledge of polychlorinated biphenyl (PCB) bioactivation and polycyclic aromatic hydrocarbon (PAH)-induced DNA damage to ras gene activation in liver tumors from dragonets exposed to these environmental carcinogens. We identified a...

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PMID: 9496912

Genes

PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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