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Article

Genotoxic effects of bitumen fumes in Big Blue transgenic rat lung.

Mutation research - 11 Apr 2006

Bottin Marie Claire, Gate Laurent, Rihn Bertrand, Micillino Jean Claude, Nathalie Monhoven, Martin Aurélie, Nunge Hervé, Morel Georges, Wrobel Richard, Ayi-Fanou Lucie, Champmartin Catherine, Keith Gérard, Binet Stéphane

Abstract excerpt

Road paving workers are exposed to bitumen fumes (CAS No. 8052-42-4), a complex mixture of volatile compounds and particles containing carcinogenic and non-carcinogenic polycyclic aromatic hydrocarbons. However, epidemiological and experimental animal studies failed to draw unambiguous conclusions concerning their toxicity. In order to gain better insights on their genotoxic potential, we used an experimental...

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Identifiers

PMID: 16457858
DOI: 10.1016/j.mrfmmm.2005.12.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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