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Article

Mutagenicity of furan in female Big Blue B6C3F1 mice.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 Aug 2014

Terrell Ashley N, Huynh Mailee, Grill Alex E, Kovi Ramesh C, O'Sullivan M Gerard, Guttenplan Joseph B, Ho Yen-Yi, Peterson Lisa A

Abstract excerpt

Furan is an abundant food and environmental contaminant that is a potent liver carcinogen in rodent models. To determine if furan is genotoxic in vivo, female B6C3F1 Big Blue transgenic mice were treated with 15 mg/kg bw furan by gavage 5 days a week for 6 weeks, or once weekly for 3 weeks. Liver cII transgene mutation-frequency and mutation spectra were determined. Furan did not increase the mutation frequency...

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Identifiers

PMID: 25344163
DOI: 10.1016/j.mrgentox.2014.04.024
PMCID: PMC4209239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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