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Evaluation of cII mutations in lung of male Big Blue mice exposed by inhalation to vanadium pentoxide for up to 8 weeks.

Mutation research. Genetic toxicology and environmental mutagenesis - 1 Aug 2015

Manjanatha Mugimane G, Shelton Sharon D, Haber Lynne, Gollapudi Bhaskar, MacGregor Judith A, Rajendran Narayanan, Moore Martha M

Abstract excerpt

Chronic inhalation of vanadium pentoxide (V2O5) increases the incidence of alveolar/bronchiolar tumors in male and female B6C3F1 mice at 1, 2, or 4 mg/m(3). The genotoxicity of V2O5 has been extensively investigated in the literature with mixed results. In general, tests for gene mutations have been negative. Both positive and negative results were reported for clastogenicity in vitro with some reports suggesting...

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PMID: 26232257
DOI: 10.1016/j.mrgentox.2015.06.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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