Article
Spectrum of mutations in kidney, stomach, and liver from lacI transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate.
Environmental and molecular mutagenesis - 1 Jan 1996
de Boer J G, Mirsalis J C, Provost G S, Tindall K R, Glickman B W
Abstract excerpt
The flame retardant tris(2,3-dibromopropyl)phosphate (TDBP), once used in cotton sleep wear for children, is presently banned from commerce. It produces tumors in rodents in both a sex- and tissue-specific manner. The kidney is the main target for tumor formation in male and female rats, as well...
Topics
- Animals
- Bacterial Proteins
- Escherichia coli Proteins
- Gastric Mucosa
- Kidney
- Lac Repressors
- Liver
- Male
- Mice
- Mice, Transgenic
- Mutation
- Organophosphates
- Repressor Proteins
- Sequence Analysis, DNA
- Stomach