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Article

GATA5 activation of the progesterone receptor gene promoter in breast cancer cells is influenced by the +331G/A polymorphism.

Cancer research - 1 Feb 2006

Huggins Gordon S, Wong Jason Y Y, Hankinson Susan E, De Vivo Immaculata

Abstract excerpt

Previously, a modest association was observed between the progesterone receptor +331G/A gene variant and breast cancer risk. Here, in a larger sample of breast cancer cases and controls (n = 1,322/n = 1,953) nested in the Nurses' Health Study cohort, we confirm a significant association (odds ratio, 1.41; 95% confidence interval, 1.10-1.79) and suggest a molecular model. The association of the +331G/A variant...

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Source

Identifiers

PMID: 16452193
DOI: 10.1158/0008-5472.CAN-05-2715

Genes

GATA5
GATA3
GATA4
GATA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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GATA5 activation of the progesterone receptor gene promoter in breast cancer cells is influenced by the +331G/A polymorphism.PMID 16452193Read ↗

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