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Article

Association of +331G/A PgR polymorphism with susceptibility to female reproductive cancer: evidence from a meta-analysis.

PloS one - 1 Jan 2013

Chaudhary Sanjib, Panda Aditya K, Mishra Dipti Ranjan, Mishra Sandip K

Abstract excerpt

The progesterone receptor (PgR), a sex steroid hormone receptor that binds progesterone is critical for normal breast development. The PgR (+331G/A, rs10895068) promoter polymorphism is associated with cancer risk possibly by altering the expression of progesterone receptor B isoform. Previous studies have provided inconsistent results. To validate the association between the PgR +331G/A polymorphism and female...

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Identifiers

PMID: 23349706
DOI: 10.1371/journal.pone.0053308
PMCID: PMC3551904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of +331G/A PgR polymorphism with susceptibility to female reproductive cancer: evidence from a meta-analysis.PMID 23349706Read ↗

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Association of the +331G/A progesterone receptor gene (PgR) polymorphism with risk of endometrial cancer in Caucasian women: a meta-analysis.Semantic proximity Read ↗

Association of a progesterone receptor gene +331 G/A polymorphism with breast cancer risk: a meta-analysis.Semantic proximity Read ↗

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Association of the PROGINS PgR polymorphism with susceptibility to female reproductive cancer: A meta-analysis of 30 studies.Semantic proximity Read ↗

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PGR +331 A/G and increased risk of epithelial ovarian cancer.Semantic proximity Read ↗

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A functional polymorphism in the progesterone receptor gene is associated with an increase in breast cancer risk.Semantic proximity Read ↗

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