Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status.

doi:10.1158/1055-9965.EPI-07-0449

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Article

Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2007

Garcia-Closas Montserrat, Troester Melissa A, Qi Ying, Langerød Anita, Yeager Meredith, Lissowska Jolanta, Brinton Louise, Welch Robert, Peplonska Beata, Gerhard Daniela S, Gram Inger Torhild, Kristensen Vessela, Børresen-Dale Anne-Lise, Chanock Stephen, Perou Charles M

Abstract excerpt

GATA-binding protein 3 (GATA3) is a transcription factor and a putative tumor suppressor that is highly expressed in normal breast luminal epithelium and estrogen receptor alpha (ER)-positive breast tumors. We hypothesized that common genetic variation in GATA3 could influence breast carcinogenesis. Four tag single-nucleotide polymorphisms (SNP) in GATA3 and its 3' flanking gene FLJ4598 were genotyped in two case...

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PMID: 18006915
DOI: 10.1158/1055-9965.EPI-07-0449

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GATA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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