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Article

Functional characterization of annexin A5 gene promoter allelic variants.

Thrombosis research - 1 Aug 2016

Tiscia Giovanni Luca, Dørum Elisabeth, Myklebust Christiane Filion, Grandone Elvira, Sandset Per Morten, Skretting Grethe

Abstract excerpt

BACKGROUND: M1 and M2 haplotypes are defined by 4 consecutive allelic variants in regulatory regions of the annexin A5 gene and have been found to reduce promoter activity. To date, no research has been carried out to investigate differential and individual impact each of the allelic variants has on promoter activity. In the current study, we functionally characterized the M1 and M2 haplotype allelic variants...

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Share to Annexin A5
Share to Cell Line
Share to Electrophoretic Mobility Shift Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Haplotypes

Share to Placenta

Share to Pregnancy

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 27318245
DOI: 10.1016/j.thromres.2016.06.009

Genes

ANXA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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