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Article

Calculation of multipoint likelihoods using flanking marker data: a simulation study.

BMC genetics - 30 Dec 2005

George Andrew W, Mangin LaVonne A, Bartlett Christopher W, Logue Mark W, Segre Alberto M, Vieland Veronica J

Abstract excerpt

The calculation of multipoint likelihoods is computationally challenging, with the exact calculation of multipoint probabilities only possible on small pedigrees with many markers or large pedigrees with few markers. This paper explores the utility of calculating multipoint likelihoods using data on markers flanking a hypothesized position of the trait locus. The calculation of such likelihoods is often feasible,...

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Identifiers

PMID: 16451655
DOI: 10.1186/1471-2156-6-S1-S44
PMCID: PMC1866740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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