Article
Efficient computation of genotype probabilities for loci with many alleles: II. Iterative method for large, complex pedigrees.
Journal of animal science - 1 Jan 2001
Thallman R M, Bennett G L, Keele J W, Kappes S M
Abstract excerpt
An algorithm for computing genotype probabilities for marker loci with many alleles in large, complex pedigrees with missing marker data is presented. The algorithm can also be used to calculate grandparental origin probabilities, which summarize the segregation pattern and are useful for mapping quantitative trait loci. The algorithm is iterative and is based on peeling on alleles instead of the traditional...
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