Article
Comparison of a multipoint identity-by-descent method with parametric multipoint linkage analysis for mapping quantitative traits.
American journal of human genetics - 1 Mar 1992
Goldgar D E, Oniki R S
Abstract excerpt
We previously developed a method of partitioning genetic variance of a quantitative trait to loci in specific chromosomal regions. In this paper, we compare this method--multipoint IBD (identical by descent) method (MIM)--with parametric multipoint linkage analysis (MLINK). A simulation study was performed comparing the methods for the major-locus, mixed, and two-locus models. The criterion for comparisons...
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