Article
Which strategy is better for linkage analysis: single-nucleotide polymorphisms or microsatellites? Evaluation by identity-by-state-identity-by-descent transformation affected sib-pair method on GAW14 data.
BMC genetics - 30 Dec 2005
Yue Qingqi, Apprey Victor, Bonney George E
Abstract excerpt
The central issue for Genetic Analysis Workshop 14 (GAW14) is the question, which is the better strategy for linkage analysis, the use of single-nucleotide polymorphisms (SNPs) or microsatellite markers? To answer this question we analyzed the simulated data using Duffy's SIB-PAIR program, which...
Topics
- Chromosome Mapping
- Congresses as Topic
- Humans
- Microsatellite Repeats
- Pedigree
- Polymorphism, Single Nucleotide
- Reproducibility of Results
- Siblings