Article
A normalized identity-by-state statistic for linkage analysis of sib pairs.
Genetic epidemiology - 1 Jan 1999
Nemesure B B, He Q, Mendell N R
Abstract excerpt
A sib-pair analysis was performed on a simulated data set for a fictitious disease, with a prevalence of approximately 3% to 6%. The disease could manifest itself in a severe or mild form and the analyses focused primarily on families with the mild form, barring any misdiagnoses. The numbers of s...
Topics
- Alleles
- Environment
- Genetic Linkage
- Genetic Markers
- Genetic Testing
- Genotype
- Humans
- Models, Genetic
- Models, Statistical
- Multifactorial Inheritance
- Nuclear Family