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Article

Parametric model-based statistics for possible genotyping errors and sample stratification in sibling-pair SNP data.

Genetic epidemiology - 1 Jan 2010

Korostishevsky Michael, Malkin Ida, Spector Tim, Livshits Gregory

Abstract excerpt

The detection of genotyping errors, based on apparent Mendelian incompatibilities in a sample of sib-pairs, is a complicated problem. In the case of a single marker and unknown parental genotypes, all combinations of sib-pair genotypes are self-consistent. Moreover, the observed deviation from equilibrium genotype frequencies may result from genotyping errors as well as from the sample's stratification. This in...

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PMID: 19455577
DOI: 10.1002/gepi.20431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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