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Article

Linkage analysis of the GAW14 simulated dataset with microsatellite and single-nucleotide polymorphism markers in large pedigrees.

BMC genetics - 30 Dec 2005

Yang Xiaohong Rose, Jacobs Kevin, Kerstann Kimberly F, Bergen Andrew W, Goldstein Alisa M, Goldin Lynn R

Abstract excerpt

Recent studies have suggested that a high-density single nucleotide polymorphism (SNP) marker set could provide equivalent or even superior information compared with currently used microsatellite (STR) marker sets for gene mapping by linkage. The focus of this study was to compare results obtained from linkage analyses involving extended pedigrees with STR and single-nucleotide polymorphism (SNP) marker sets. We...

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PMID: 16451599
DOI: 10.1186/1471-2156-6-S1-S14
PMCID: PMC1866796

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NPL

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