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Article

Is there a folate-related gene-environment interaction in the etiology of childhood acute lymphoblastic leukemia?

International journal of cancer - 1 Jul 2006

Milne Elizabeth, de Klerk Nicholas H, van Bockxmeer Frank, Kees Ursula R, Thompson Judith R, Baker David, Armstrong Bruce K

Abstract excerpt

Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer in developed countries. Little is known about its causes, although its early age at diagnosis has focused interest on maternal and perinatal factors. We have previously observed a protective effect of maternal folate supplementation during pregnancy against ALL, and a number of studies have reported protective effects of some common...

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PMID: 16450391
DOI: 10.1002/ijc.21803

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Is there a folate-related gene-environment interaction in the etiology of childhood acute lymphoblastic leukemia?PMID 16450391Read ↗

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