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Article

Role of MTHFR genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia.

Blood - 1 Jan 2004

Krajinovic Maja, Lamothe Stephanie, Labuda Damian, Lemieux-Blanchard Emilie, Theoret Yves, Moghrabi Albert, Sinnett Daniel

Abstract excerpt

The central role of methylenetetrahydrofolate reductase (MTHFR) in the folate metabolism renders MTHFR gene polymorphisms (C677T and A1298C) potential modulators of a variety of disorders whose development depends on folate/homocysteine imbalance. Here, we provide additional evidence on the prote...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 12958073
DOI: 10.1182/blood-2003-06-1794

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12958073-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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