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Article

Association of the -1438G/A polymorphism of the 5-HT2A receptor gene with obstructive sleep apnea syndrome.

ORL; journal for oto-rhino-laryngology and its related specialties - 1 Jan 2006

Bayazit Yildirim A, Yilmaz Metin, Ciftci Tansu, Erdal Emin, Kokturk Oguz, Gokdogan Tuba, Kemaloglu Yusuf K, Inal Erdogan

Abstract excerpt

OBJECTIVE: Serotonergic neurons innervating motoneurons increase their firing rates in response to respiratory challenges, and long-term facilitation of respiratory activity in response to hypoxia is serotonin (5-HT) dependent. Polymorphism of the genes which code for 5-HT receptors may affect functions of the serotonergic system, and may be associated with obstructive sleep apnea syndrome (OSAS). The objective...

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Identifiers

PMID: 16449821
DOI: 10.1159/000091216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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