Article
Polymorphisms in the 5-HTR2A gene related to obstructive sleep apnea syndrome.
Brazilian journal of otorhinolaryngology - 1 Jun 2011
Piatto Vânia Belintani, Carvalho Thiago Bittencourt Ottoni de, De Marchi Nely Silva Aragão, Molina Fernando Drimel, Maniglia José Victor
Abstract excerpt
UNLABELLED: Obstructive sleep apnea syndrome (OSAS) is one of the most complex disorders of sleep; it involves several genetic factors that contribute to the phenotype. Serotonin (5-HT) regulates a variety of visceral and physiological functions, including sleep. Gene 5-HTR2A polymorphisms may change the transcription of several receptors in the serotoninergic system, thereby contributing to OSAS. AIM: To...
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