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Article

The association of 5-HT2A, 5-HTT, and LEPR polymorphisms with obstructive sleep apnea syndrome: a systematic review and meta-analysis.

PloS one - 1 Jan 2014

Qin Baodong, Sun Zhen, Liang Yan, Yang Zaixing, Zhong Renqian

Abstract excerpt

OBJECTIVE: A consensus has not been reached regarding the association of several different gene polymorphisms and susceptibility to obstructive sleep apnea syndrome (OSAS). We performed a meta-analysis to better evaluate the associations between 5-HT2A, 5-HTT, and LEPR polymorphisms, and OSAS. METHOD: 5-HT2A, 5-HTT, and LEPR polymorphisms and OSAS were identified in PubMed and EMBASE. The pooled odd rates (ORs)...

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Source

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Identifiers

PMID: 24755731
DOI: 10.1371/journal.pone.0095856
PMCID: PMC3995918

Genes

LEPR
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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