Article
Relationship of obstructive sleep apnea syndrome with the 5-HT2A receptor gene in Brazilian patients.
Sleep & breathing = Schlaf & Atmung - 1 Mar 2013
de Carvalho Thiago Bittencourt Ottoni, Suman Marcela, Molina Fernando Drimel, Piatto Vânia Belintani, Maniglia José Victor
Abstract excerpt
BACKGROUND: Serotonin (5-HT) regulates a variety of visceral and physiological functions, including sleep. Polymorphisms in the 5-HT2A receptor gene can alter its transcription, affecting the number of receptors in the serotoninergic system, contributing to obstructive sleep apnea syndrome (OSAS). OBJECTIVE: The aim of this study was to determine the prevalence of the 102T-C and -1438G-A polymorphisms in the...
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