Article
Association of the 5-HT2A receptor gene polymorphisms with obstructive sleep apnea hypopnea syndrome in Chinese Han population.
Acta oto-laryngologica - 1 Feb 2012
Yin Guoping, Ye Jingying, Han Demin, Zhang Yuhuan, Zeng Wotan, Liang Chen
Abstract excerpt
CONCLUSIONS: The -1438G/A polymorphism of 5-HT2A receptor gene may associate with obstructive sleep apnea hypopnea syndrome (OSAHS) in a Chinese Han population. Different genotypes of -1438G/A polymorphism may influence the ventilatory activity in response to hypoxia, and in turn the sleep breath status. OBJECTIVE: This study was designed to assess the association of polymorphisms in all exons and promoter region...
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