Article
Association between 5-HT2A receptor polymorphisms and risk of obstructive sleep apnea and hypopnea syndrome: a systematic review and meta-analysis.
Gene - 10 Nov 2013
Zhao Yanhui, Tao Li, Nie Ping, Lu Xiaofeng, Xu Xiaolong, Chen Jindong, Zhu Min
Abstract excerpt
Obstructive sleep apnea and hypopnea syndrome (OSAHS) is a common disorder with several predisposing factors, which may include genetic causes. Studies of the association of susceptibility to and severity of OSAHS with the polymorphisms of the 5-HTR 2A/2C genes have had low statistical power and have yielded inconsistent results. To clarify the association we perform a meta-analysis that combines the genotyping...
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