Article
Association between the -1438G/A and T102C polymorphisms of 5-HT2A receptor gene and obstructive sleep apnea: a meta-analysis.
Molecular biology reports - 1 Nov 2013
Wu Ying, Liu Hong-Bing, Ding Ming, Liu Jian-Nan, Zhu Xuan-Feng, Gu Jian-Hua, Lu Gan
Abstract excerpt
The serotonin 2A (5-HT2A) receptor has been implicated in obstructive sleep apnea (OSA). Single nucleotide polymorphisms (SNPs) in the 5-HT2A gene have been found in OSA, the most common being -1438G/A and T102C; however, studies of the association between 5-HT2A SNPs and OSA risk have reported inconsistent findings. A meta-analysis was performed to quantitatively review the association between -1438G/A and T102C...
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