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Article

Serotonin-2A and 2C receptor gene polymorphisms in Japanese patients with obstructive sleep apnea.

Internal medicine (Tokyo, Japan) - 1 Sept 2005

Sakai Kunihiko, Takada Toshinori, Nakayama Hideaki, Kubota Yukiko, Nakamata Masami, Satoh Makoto, Suzuki Eiichi, Akazawa Kohei, Gejyo Fumitake

Abstract excerpt

OBJECTIVE: The serotonin (5-HT) 2A and 2C receptor subtype plays an important role in the maintenance of upper airway stability and normal breathing in obesity. Polymorphisms in the 5-HT 2A receptor gene (HTR2A) and 5-HT 2C receptor gene (HTR2C) are associated with various diseases. The aim of th...

Topics

Adult
Alleles
Base Sequence
Case-Control Studies
DNA
Gene Frequency
Genotype
Humans
Japan
Male
Middle Aged
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Receptor, Serotonin, 5-HT2A

Receptor, Serotonin, 5-HT2C

Sleep Apnea, Obstructive

Source

Identifiers

PMID: 16258205
DOI: 10.2169/internalmedicine.44.928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-16258205-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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