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Article

p53 gene alternation in squamous cell carcinoma of the esophagus detected by PCR-cold SSCP analysis.

Proceedings of the National Science Council, Republic of China. Part B, Life sciences - 1 Jul 1998

Wang L S, Chow K C, Liu C C, Chiu J H

Abstract excerpt

Mutations of the p53 tumor suppressor gene play an important role in the development of common human malignancies. Previous reports revealed that the frequencies of p53 alternations in esophageal carcinoma varied from 26% to 87%. The clinical significance of p53 alternations is still disputed. In the present study, we used polymerase chain reaction--"cold" single-strand conformation polymorphism (PCR-"cold"...

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PMID: 9779600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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