p53 gene alternation in squamous cell carcinoma of the esophagus detected by PCR-cold SSCP analysis.

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Article

p53 gene alternation in squamous cell carcinoma of the esophagus detected by PCR-cold SSCP analysis.

Proceedings of the National Science Council, Republic of China. Part B, Life sciences - 1 Jul 1998

Wang L S, Chow K C, Liu C C, Chiu J H

Abstract excerpt

Mutations of the p53 tumor suppressor gene play an important role in the development of common human malignancies. Previous reports revealed that the frequencies of p53 alternations in esophageal carcinoma varied from 26% to 87%. The clinical significance of p53 alternations is still disputed. In...

Topics

Age Factors
Aged
Carcinoma, Squamous Cell
Cell Differentiation
Esophageal Neoplasms
Esophagus
Exons
Female
Genes, p53
Humans
Lymphatic Metastasis
Male
Middle Aged
Mucous Membrane
Mutation
Neoplasm Invasiveness
Neoplasm Staging
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 9779600

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9779600-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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