A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid.

doi:10.1016/0378-1119(92)90482-5

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Article

A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid.

Gene - 1 Aug 1992

Parris C N, Seidman M M

Abstract excerpt

We have developed a new shuttle vector plasmid for studying mutagenesis in mammalian cells that permits proof of independence of identical mutations. Mutations occur more frequently at some sites in a gene than in others, and in a collection of mutant plasmids from a single transfection of mammal...

Topics

Base Sequence
Cell Line, Transformed
DNA
Genetic Vectors
Humans
Molecular Sequence Data
Mutation
Plasmids
Ultraviolet Rays
Xeroderma Pigmentosum

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