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Article

The fork head transcription factor FKTF-1b from Strongyloides stercoralis restores DAF-16 developmental function to mutant Caenorhabditis elegans.

International journal for parasitology - 1 Mar 2006

Massey Holman C, Bhopale Mahendra K, Li Xinshe, Castelletto Michelle, Lok James B

Abstract excerpt

The purpose of this study was to determine whether Strongyloides stercoralis FKTF-1, a transcription factor of the FOXO/FKH family and the likely output of insulin/IGF signal transduction in that parasite, has the same or similar developmental regulatory capabilities as DAF-16, its structural ortholog in Caenorhabditis elegans. To this end, both splice variants of the fktf-1 message were expressed under the...

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Identifiers

PMID: 16442538
DOI: 10.1016/j.ijpara.2005.11.007
PMCID: PMC3638016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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