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DAF-16: FOXO in the Context of C. elegans.

Current topics in developmental biology - 1 Jan 2018

Tissenbaum Heidi A

Abstract excerpt

In Caenorhabditis elegans, there is a single FOXO transcription factor homolog, encoded by the gene, daf-16. As a central regulator for multiple signaling pathways, DAF-16 integrates these signals which results in modulation of several biological processes including longevity, development, fat storage, stress resistance, innate immunity, and reproduction. Using C. elegans allows for studies of FOXO in the context...

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Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Nucleus
Forkhead Transcription Factors
Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

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PMID: 29433733
DOI: 10.1016/bs.ctdb.2017.11.007

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