Article
daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans.
Science (New York, N.Y.) - 14 Nov 1997
Lin K, Dorman J B, Rodan A, Kenyon C
Abstract excerpt
The wild-type Caenorhabditis elegans nematode ages rapidly, undergoing development, senescence, and death in less than 3 weeks. In contrast, mutants with reduced activity of the gene daf-2, a homolog of the insulin and insulin-like growth factor receptors, age more slowly than normal and live mor...
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