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Article

Verbal paired-associate learning by APOE genotype in non-demented older adults: fMRI evidence of a right hemispheric compensatory response.

Neurobiology of aging - 1 Feb 2007

Han S Duke, Houston Wes S, Jak Amy J, Eyler Lisa T, Nagel Bonnie J, Fleisher Adam S, Brown Gregory G, Corey-Bloom Jody, Salmon David P, Thal Leon J, Bondi Mark W

Abstract excerpt

Previous studies of episodic memory report a greater extent of blood-oxygenation-level-dependent (BOLD) response in non-demented older adults with the apolipoprotein E epsilon-4 (APOE epsilon4) allele than in those without the allele. We conducted a functional MRI study to investigate whether APOE genotype is related to brain response to verbal paired-associate encoding and consolidation, particularly in the...

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Source

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Identifiers

PMID: 16434125
DOI: 10.1016/j.neurobiolaging.2005.12.013
PMCID: PMC1705815

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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