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Article

Reduced hippocampal volume in non-demented carriers of the apolipoprotein E epsilon4: relation to chronological age and recognition memory.

Neuroscience letters - 20 Mar 2006

Lind Johanna, Larsson Anne, Persson Jonas, Ingvar Martin, Nilsson Lars-Göran, Bäckman Lars, Adolfsson Rolf, Cruts Marc, Sleegers Kristel, Van Broeckhoven Christine, Nyberg Lars

Abstract excerpt

Apolipoprotein E epsilon4 (APOE epsilon4) is the main known genetic risk factor for Alzheimer's disease (AD). Some previous studies have reported structural brain changes as well as cognitive deficits in non-demented APOE epsilon4 carriers, but the pattern of results is inconsistent and studies with larger sample sizes have been called for. Here we compared hippocampal volume and recognition-memory performance...

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Identifiers

PMID: 16406347
DOI: 10.1016/j.neulet.2005.11.070

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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