Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial aggregation of aspirin-induced urticaria and leukotriene C synthase allelic variant.

The British journal of dermatology - 1 Feb 2006

Mastalerz L, Setkowicz M, Sanak M, Rybarczyk H, Szczeklik A

Abstract excerpt

BACKGROUND: We have reported that in patients with chronic idiopathic urticaria (CIU) who reacted adversely to aspirin, the frequency of the (-444)C allele of the leukotriene C(4) synthase gene (LTC4S) was higher than in patients who tolerated aspirin well. OBJECTIVES: To study the pattern of aspirin-induced urticaria (AIU) in two families, with special interest on the polymorphisms of LTC4S (AA, AC, CC) and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Aspirin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclooxygenase Inhibitors

Share to Drug Eruptions

Share to Glutathione S-Transferase pi

Share to Glutathione Transferase

Share to Single-Blind Method

Share to Urticaria

Source

Identifiers

PMID: 16433794
DOI: 10.1111/j.1365-2133.2005.06851.x

Genes

GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial aggregation of aspirin-induced urticaria and leukotriene C synthase allelic variant.PMID 16433794Read ↗

The A-444C polymorphism in the leukotriene C4 synthase gene is associated with aspirin-induced urticaria.Semantic proximity Read ↗

Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma.Semantic proximity Read ↗

What do we know about the genetics of aspirin intolerance?Semantic proximity Read ↗

Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma.Semantic proximity Read ↗

Genetic variability of prostaglandin E2 receptor subtype EP4 gene in aspirin-intolerant chronic urticaria.Semantic proximity Read ↗

Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population.Semantic proximity Read ↗

Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics.Semantic proximity Read ↗

Pharmacogenomics in aspirin intolerance.Semantic proximity Read ↗

5' flanking region polymorphism of the gene encoding leukotriene C4 synthase does not correlate with the aspirin-intolerant asthma phenotype in the United States.Semantic proximity Read ↗

Enhanced expression of the leukotriene C(4) synthase due to overactive transcription of an allelic variant associated with aspirin-intolerant asthma.Semantic proximity Read ↗

Genetic markers for differentiating aspirin-hypersensitivity.Semantic proximity Read ↗

Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.