Article
Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma.
The Journal of allergy and clinical immunology - 1 Apr 2004
Mastalerz Lucyna, Setkowicz Malgorzta, Sanak Marek, Szczeklik Andrew
Abstract excerpt
BACKGROUND: Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) can precipitate adverse reactions in two apparently different clinical conditions: bronchial asthma and chronic idiopathic urticaria (CIU). Recent evidence indicates that the reactions are triggered by the drugs that inhibit cyclooxygenase-1 but not cyclooxygenase-2. OBJECTIVE: To assess whether patients with CIU and aspirin sensitivity...
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