Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

What do we know about the genetics of aspirin intolerance?

Journal of clinical pharmacy and therapeutics - 1 Oct 2008

Palikhe N S, Kim S-H, Park H-S

Abstract excerpt

Although acetylsalicylic acid is prescribed for a broad range of diseases, it can induce a wide array of clinically recognized hypersensitivity reactions, including aspirin-intolerant asthma (AIA) with rhinitis and aspirin-intolerant urticaria (AIU) with anaphylaxis. Altered eicosanoid metabolism is the generally accepted mechanism of aspirin intolerance; the overproduction of cysteinyl leucotrienes has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspirin
Share to Asthma
Share to Anti-Inflammatory Agents, Non-Steroidal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Hypersensitivity

Share to ALOX5 gene

Share to Genetic Markers

Share to Polymorphism, Single Nucleotide

Share to Urticaria

Source

Identifiers

PMID: 18834360
DOI: 10.1111/j.1365-2710.2008.00961.x

Genes

ALOX5
HNMT
TBX21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

What do we know about the genetics of aspirin intolerance?PMID 18834360Read ↗

Genetic markers for differentiating aspirin-hypersensitivity.Semantic proximity Read ↗

Pharmacogenetics of Aspirin-Intolerant AsthmaSemantic proximity Read ↗

Update on recent advances in the management of aspirin exacerbated respiratory disease.Semantic proximity Read ↗

Physiopathology and genetics in aspirin-exacerbated respiratory disease.Semantic proximity Read ↗

Genetic variability of prostaglandin E2 receptor subtype EP4 gene in aspirin-intolerant chronic urticaria.Semantic proximity Read ↗

Unraveling the Genetic Basis of Aspirin Hypersensitivity in Asthma Beyond Arachidonate PathwaysSemantic proximity Read ↗

Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma.Semantic proximity Read ↗

Pharmacogenomics in aspirin intolerance.Semantic proximity Read ↗

Genetic basis of hypersensitivity reactions to nonsteroidal anti-inflammatory drugsSemantic proximity Read ↗

Leukotriene-related gene polymorphisms in patients with aspirin-intolerant urticaria and aspirin-intolerant asthma: differing contributions of ALOX5 polymorphism in Korean population.Semantic proximity Read ↗

Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics.Semantic proximity Read ↗

Genetic variants associated with drugs-induced immediate hypersensitivity reactions: a PRISMA-compliant systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.