Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Amplicon DNA melting analysis for mutation scanning and genotyping: cross-platform comparison of instruments and dyes.

Clinical chemistry - 1 Mar 2006

Herrmann Mark G, Durtschi Jacob D, Bromley L Kathryn, Wittwer Carl T, Voelkerding Karl V

Abstract excerpt

BACKGROUND: DNA melting analysis for genotyping and mutation scanning of PCR products by use of high-resolution instruments with special "saturation" dyes has recently been reported. The comparative performance of other instruments and dyes has not been evaluated. METHODS: A 110-bp fragment of the beta-globin gene including the sickle cell anemia locus (A17T) was amplified by PCR in the presence of either the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benzothiazoles
Share to Diamines
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Fluorescent Dyes

Share to Globins

Share to Organic Chemicals

Share to Quinolines

Source

Identifiers

PMID: 16423901
DOI: 10.1373/clinchem.2005.063438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Amplicon DNA melting analysis for mutation scanning and genotyping: cross-platform comparison of instruments and dyes.PMID 16423901Read ↗

Expanded instrument comparison of amplicon DNA melting analysis for mutation scanning and genotyping.Semantic proximity Read ↗

Sensitivity and specificity of single-nucleotide polymorphism scanning by high-resolution melting analysis.Semantic proximity Read ↗

High-resolution DNA melting analysis for simultaneous mutation scanning and genotyping in solution.Semantic proximity Read ↗

Closed-tube genotyping with unlabeled oligonucleotide probes and a saturating DNA dye.Semantic proximity Read ↗

Rapid and sensitive detection of BRCA1/2 mutations in a diagnostic setting: comparison of two high-resolution melting platforms.Semantic proximity Read ↗

High-resolution genotyping by amplicon melting analysis using LCGreen.Semantic proximity Read ↗

Genotyping accuracy of high-resolution DNA melting instruments.Semantic proximity Read ↗

High resolution melting analysis for gene scanning.Semantic proximity Read ↗

High-resolution melting analysis of single nucleotide polymorphisms.Semantic proximity Read ↗

Genotyping of single-nucleotide polymorphisms by high-resolution melting of small amplicons.Semantic proximity Read ↗

High resolution melting applications for clinical laboratory medicine.Semantic proximity Read ↗

Simultaneous mutation scanning and genotyping by high-resolution DNA melting analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.