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Article

High-resolution genotyping by amplicon melting analysis using LCGreen.

Clinical chemistry - 1 Jun 2003

Wittwer Carl T, Reed Gudrun H, Gundry Cameron N, Vandersteen Joshua G, Pryor Robert J

Abstract excerpt

BACKGROUND: High-resolution amplicon melting analysis was recently introduced as a closed-tube method for genotyping and mutation scanning (Gundry et al. Clin Chem 2003;49:396-406). The technique required a fluorescently labeled primer and was limited to the detection of mutations residing in the melting domain of the labeled primer. Our aim was to develop a closed-tube system for genotyping and mutation scanning...

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PMID: 12765979
DOI: 10.1373/49.6.853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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